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RERF's Research

Genetic Study

Genetic study, consisting of cytogenetic research and molecular genetic research, is largely carried out by the Department of Genetics.
Cytogenetic Research
Individual radiation doses are assessed by evaluation of chromosome aberration frequency in the blood cells of A-bomb survivors. Radiation doses can also be estimated with special techniques that measure trace amounts of radicals that remain in the teeth of A-bomb survivors.

Molecular Genetic Research
By evaluating DNA from parents and children, studies are carried out to determine whether de novo mutation rates are increased among the children of A-bomb survivors. Efforts are also being made to accurately detect radiation-induced mutation rates using mouse models. Studies have been initiated to examine genomic instability (marked by high-frequency genome-wide changes) and genetic effects on cancer (association between radiation exposure and individual genetic characteristics).